HBOT

HBOT

What does Hyperbaric oxygen do?

Physicists figured out years ago that a gas under pressure is more likely to dissolve into liquid.  In mild hyperbaric oxygen therapy, the gas is oxygen and the liquid is blood. But under pressure, oxygen does not just hook up to red blood cells the way were used to thinking about it, it also dissolves into the plasma. When that plasma circulates near dormant or injured tissue such as an autistic brain, a bruised muscle, a sprained tendon, or a surgical wound, the oxygen in the plasma dissolves further into the damaged area than the oxygen that is attached to the red blood cell in the conventional delivery system can.  During an HBOT session, there is substantial increase in the amount of oxygen carried in all body fluids, including plasma, cerebrospinal fluid, lymph and intracellular fluids. The increased pressure (1.3 times the atmospheric pressure) causes an increase of up to 2,000% in plasma oxygen concentrations with a resultant increase in tissue oxygenation. This allows increased oxygen levels even in areas with poor or compromised blood, as well as in areas of tissue oxygenation. The effect is delivered via the lungs to the developing capillary bed where it helps capillaries proliferate white blood cells and fibroblasts create new tissue. It can reach bone and tissue, which are inaccessible to the blood cells, enhance white blood cells, enhance white blood cell function, and promote the formation of new capillary and peripheral blood vessels. This may result in increased infection control and faster healing of a wide range of conditions.

How much is too little and how much is too much?

Oxygen comprises approximately 21% of the air we breathe and it loads 93-98% of your red blood cells with oxygen every time they pass through your lungs. This keeps most of us going day in and day out. A lot of oxygen is approximately 99%, or what is what delivered by oxygen tanks to divers or others using oxygen, as well as what they use in high pressure hard shell chambers at hospitals.  It is potentially explosive and can be toxic to your body if you get too much for too long. Higher pressures and high levels of oxygen can be necessary when treating a diver who has "the bends" and certain wounds that will not heal. But the world of hyperbaric medicine is learning that lower pressures and less oxygen seem to have excellent effect on multiple systems of our bodies. In particular, lower pressure appears to be more beneficial for the injured brain than higher pressure.

So, how much is just right?

Somewhere in between too little and too much is what the mild hyperbaric chamber does. It pressurizes us to 1.3 times the atmospheric pressure, effectively like going to the bottom of an 11 foot swimming pool and hanging out there with air to breathe and ears that are equalized. The experience feels like what happens when a pilot pressurizes an airplane cabin. When we fly, they increase the cabin pressure to maintain something close to room air for us while we are at altitude in the "thin," oxygen-poor air of our friendly skies.

When we use a concentrator, we enrich the air in the chamber with oxygen.  The concentrator removes most of the nitrogen that is in room air delivering more concentrated O2 through a small accessory tube to which we can attach a mask. The end result is significantly more than 21% O2 and less than 100% O2, and will vary depending on whether or not a client is wearing a mask or simply near the accessory oxygen.  Lower pressures and smaller increases in oxygen content like the environment generated in the mild chamber seem to be ideal for promoting healing of dormant and injured cells.

If a little is good, more is not necessarily better

Remember that a little oxygen is good, too much oxygen is toxic and can actually induce oxidative stress (impairing healing of any sort), and in between there somewhere is superb. This is true because the human body's relationships with oxygen are almost all curvilinear- sigmoid "s" shapes, bell curves that start low, go high, and come back down low with increasing numbers across the bottom of the graph, so that there can actually be a bad effect from too much. If a little is good, more is not necessarily better is an important concept in mild hyperbaric oxygen therapy.

How does the increase in oxygen help?

Remember that first paragraph where increased pressure dissolved more oxygen into the plasma in addition to loading up all of the red blood cells? When that oxygen enriched plasma circulates near dormant or injured tissue such as an autistic or encephalopathic brain, a bruised muscle, a sprained tendon, or a  wound, the oxygen dissolves further into the damaged area than the oxygen that is attached to the red blood cell in the conventional room air way. It penetrates deeper, allowing for potential healing in a place that either would not happen at all (the autistic or encephalopathic brain) or would not happen for a while until the more superficial tissue heals first (the sprains and bruises and wounds.)

How do we know the oxygen actually does some healing?

Football fans know that Terrell Owens of the Philadelphia Eagles sustained an ankle fracture at the end of the 2004-2005 season that would traditionally have required a year to rehabilitate. However, he used his own mild hyperbaric chamber along with other therapy to go from surgery to playing in the Superbowl in six weeks. His recovery was extraordinary, and he excelled on the field.

We can look to apparent healing of the brain by monitoring its perfusion and activity. We can also monitor behaviors, response to stimuli (sensory function) and motor skills. Monitoring of perfusion and activity, of the relative numbers of dormant, sleeping or alert and functioning brain cells is done with a Brain SPECT (Single Photo Emission Computed Tomography) scan. At http://www.hbot4u.com/brainscans.html you can see SPECT scan pictures of a 17 year old boy's brain who had autism, poor grades, poor social skills, and seizures. The scan looks at blood flow/activity of the brain, and it's quantified across the rainbow/spectrum of color. Purple/blue is low flow and activity- those dormant sleeping neurons, through green, and up to yellow into red with intensification to white being high flow/activity. The second set of pictures as you scroll down this web page is his brain a year after he completed 50 sessions. You can see the dramatic increases in the front of the brain where social skills "live" and the sides of the brain where language "lives"

Note that this young man's sessions were stopped after 50.  Although there was dramatic improvement in his SPECT scan, it did not "light up" all areas of the brain.  Would other areas have improved with more time? With lower pressures and less O2 in the mild chambers that are FDA approved for use in a non-hospital setting, we can potentially continue sessions, and the possibility of continued steady improvement is very real.  In fact, long term clients give testimony to ongoing improvements that constantly evolve.

Is this the magic bullet for which we have been awaiting?

Mild hyperbaric oxygen will not be the panacea. Once revitalized, the brain cells still have to be trained to do what they were intended to do (consider Neurofeedback / Brain Training) and they likely still need ongoing metabolic support (nutrition and vitamin supplementation) to complete their rehabilitation. That being said, oxygen is critical to most processes within the human body and perhaps the best description of its role will be to augment to every therapy and treatment a client is offered.

What are we doing to figure out how hyperbaric oxygen helps (with Autism)?

A myriad of research is needed. Thoughtful House, Pediatric Partners of Ponte Vedra, and the Hyperbaric Therapy Center have initiated an evaluation of how mild hyperbaric oxygen influences characteristics of autism.  Based on other SPECT scan before and after results, we anticipate that there will be improvements on these children's SPECT scans as others have seen before, and that there will be correlating improvements in their ATEC scores quantifying the plethora of parental and physician testimony to often dramatic improvement in our children.

If we indeed document these two changes on a small scale study, then one would be tempted to infer that the children who weren't scanned but did have improved ATEC scores had similar improvements in their brain flow and activity. This will prompt larger scale longer term studies and hopefully funding to support them. Once begun on this path, others will surely begin to probe into the effects on, at the least, the impact of mild hyperbaric oxygen on immune function and gut health.

So what is the bottom line?

It has been shown that various clients (not necessarily clients of SIH) have sustained benefit from 20-40 sessions of mild hyperbaric oxygen. Originally developed during the 1930’s, HBOT has long been recognized as the definitive treatment for decompression sickness, air embolism (diatrogenic and diving related) and carbon monoxide poisoning. During the last few years, HBOT has emerged as a helpful for such additional conditions as: cerebral palsy, burns, cerebral edema (brain swelling), sickle cell anemia, gangrene, near drowning, severed limbs, smoke inhalation, spinal cord injury, organic brain syndrome, stroke, coma, multiple sclerosis, hearing loss, radiation myelitis, crush injuries, soft tissue, non-healing fractures, tendon and ligament injuries, delayed wound healing, decubitus ulcers, frostbite, diabetic retinopathy, migraine and cluster headache, myocardial infarction, chronic fatigue, HIV-related fatigue, Bell’s palsy, Lyme disease, fibromyalgia, autism, Crohn’s disease, reflex sympathetic dystrophy, and osteoradionecrosis (bone degeneration after radiation exposure), to list a few. It is recommended that HBOT be used as adjunctive to medical treatments already being given to a client.
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